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Bipolar affective disorder
Author(s) -
Dewan M. J.,
Haldipur C. V.,
Boucher M. F.,
Ramachandran T.,
Major L. F.
Publication year - 1988
Publication title -
acta psychiatrica scandinavica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.849
H-Index - 146
eISSN - 1600-0447
pISSN - 0001-690X
DOI - 10.1111/j.1600-0447.1988.tb05187.x
Subject(s) - lithium carbonate , psychology , bipolar disorder , neuropsychology , thalamus , neuropsychological test , family history , psychiatry , lithium (medication) , clinical psychology , medicine , neuroscience , cognition , physics , quantum mechanics , ion , ionic bonding
— Since the clinical significance of CT abnormalities found in bipolar patients remains obscure, we studied 26 DSM‐III bipolar patients who had specific CT abnormalities (third ventricle enlargement, and hyperdensity of the caudate, thalamus, anterior frontal white matter, and right temporal lobe) on numerous parameters such as EEG, the Halstead‐Reitan Neuropsychological Battery, premorbid personality adjustment, family history of affective disorder, positive and negative symptoms, employment history, and response to lithium carbonate treatment. None of these measures could differentiate between the CT abnormal and CT normal subgroups. The implications of these findings are discussed.