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Topographical distribution of absolute alpha‐power in the EEG and psychopathology in schizophrenic outpatients
Author(s) -
Gaebel W.,
Ulrich G.
Publication year - 1988
Publication title -
acta psychiatrica scandinavica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.849
H-Index - 146
eISSN - 1600-0447
pISSN - 0001-690X
DOI - 10.1111/j.1600-0447.1988.tb05140.x
Subject(s) - absolute power , lateralization of brain function , psychology , anxiety , schizophrenia (object oriented programming) , electroencephalography , psychopathology , alpha (finance) , depression (economics) , audiology , psychiatry , clinical psychology , medicine , psychometrics , neuroscience , construct validity , politics , political science , law , economics , macroeconomics
— In 36 schizophrenic outpatients (Research Diagnostic Criteria) under neuroleptic maintenance treatment the EEG was recorded under resting conditions. The absolute alpha‐power (7.5‐13 Hz) was estimated by Fast Fourier Transform as the mean of 300 2‐second epochs for the leads F3/A1, F4/A2, 01/A2 and 02 A2. Two lateralization quotients (anterior, posterior) and two anteriorization quotients (left, right) were calculated from the absolute alpha‐power. Clinical status was assessed cross‐sectionally with BRPS, GAS and CGI. The main findings are: 1) A linear relationship between the left/right ratio of absolute alpha‐power over posterior regions and anxiety/depression — the more the alpha‐power is left‐lateralized, the higher the anxiety/depression score; 2) a curvilinear, inverted U‐shaped relationship between the left/right ratio of absolute alpha‐power over posterior regions and the score of schizophrenia‐specific symptomatology; 3) the amount of daily neuroleptic dose (mgCPZ) has no impact on EEG‐parameters. Results are discussed with respect to hemisphere asymmetry models of psychopathology.