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Antipsychotic withdrawal symptoms: Phenomenology and pathophysiology
Author(s) -
Dilsaver S. C.,
Alessi N. E.
Publication year - 1988
Publication title -
acta psychiatrica scandinavica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.849
H-Index - 146
eISSN - 1600-0447
pISSN - 0001-690X
DOI - 10.1111/j.1600-0447.1988.tb05116.x
Subject(s) - discontinuation , anxiety , nausea , psychology , anorexia , psychiatry , antipsychotic , drug withdrawal , myalgia , medicine , insomnia , anesthesia , drug , schizophrenia (object oriented programming)
— The authors review the literature discribing non‐dyskinetic antipsychotic withdrawal phenomena. Withdrawal of these agents can cause nausea, emesis, anorexia, diarrhea, rhinorrhea, diaphoresis, myalgia, paresthesia, anxiety, agitation, restlessness, and insomnia. Psychotic relapse is often presaged by increased anxiety, agitation, restlessness and insomnia, but the temporal relationship of these prodromal symptoms to reduction in the dosage or discontinuation of neuroleptics distinguishes them from the effects of abrupt withdrawal.