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Melatonin plasma response to MAO inhibitor: Influence on human pineal activity?
Author(s) -
Oxenkrug G.F.,
Balon R.,
Jain A.K.,
Mclntyre I.M.
Publication year - 1988
Publication title -
acta psychiatrica scandinavica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.849
H-Index - 146
eISSN - 1600-0447
pISSN - 0001-690X
DOI - 10.1111/j.1600-0447.1988.tb05093.x
Subject(s) - melatonin , tranylcypromine , pineal gland , endocrinology , medicine , plasma levels , human plasma , circadian rhythm , chemistry , biochemistry , monoamine oxidase , enzyme , chromatography
— Strong negative correlation has been observed between nighttime (physiological) elevation of plasma melatonin and plasma melatonin increase induced by a single dose of MAO inhibitor, tranylcypromine. The possible use of acute plasma melatonin response to MAO inhibitor as a functional test for the evaluation of human pineal activity is discussed.