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The thyrotropin response to thyrotropin‐releasing hormone as a biological marker of suicidal risk in depressive patients
Author(s) -
Kørner A.,
Kirkegaard C.,
Larsen J. K.
Publication year - 1987
Publication title -
acta psychiatrica scandinavica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.849
H-Index - 146
eISSN - 1600-0447
pISSN - 0001-690X
DOI - 10.1111/j.1600-0447.1987.tb05618.x
Subject(s) - thyrotropin releasing hormone , medicine , commit , hormone , endocrinology , stimulation , depression (economics) , psychology , suicide risk , poison control , suicide prevention , medical emergency , database , computer science , economics , macroeconomics
In order to evaluate a possible predictive value for committing suicide of a reduced thyrotropin‐stimulating hormone (TSH) response to thyrotropin‐releasing hormone (TRH) stimulation we studied 306 depressed patients. The patients were followed for a mean of 5.8 (SD 2.9) years. During this period, 18 patients committed suicide. The TSH response to TRH stimulation in these 18 patients who committed suicide was lower than in the patients who did not commit suicide. The difference is not statistically significant. It is concluded that the TSH response to TRH cannot be said to identify the patients who later commit suicide.