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Depressed mood and reality disturbance correlate with decreased nocturnal melatonin in depressed patients
Author(s) -
Brown R. P.,
Kocsis J. H.,
Caroff S.,
Amsterdam J.,
Winokur A.,
Stokes P.,
Frazer A.
Publication year - 1987
Publication title -
acta psychiatrica scandinavica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.849
H-Index - 146
eISSN - 1600-0447
pISSN - 0001-690X
DOI - 10.1111/j.1600-0447.1987.tb02895.x
Subject(s) - melatonin , depression (economics) , nocturnal , mood , medicine , disturbance (geology) , psychology , hamilton depression scale , endocrinology , psychiatry , mood disorders , significant difference , biology , anxiety , hamd , economics , macroeconomics , paleontology
The authors measured serum samples of melatonin at 11:00 p.m. in 28 patients suffering from major depression. Melatonin secretion was inversely correlated with the depressed mood and reality disturbance factors of the Hamilton Depression Scale. These results are consistent with previous reports of low melatonin syndrome in a subgroup of depressed patients.