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Effect of interrupted sleep patterns and partial sleep deprivation on DST and mood in psychiatric house officers
Author(s) -
Altshuler L. L.,
Kagan B. L.,
Baxter L. R.,
Smith G.,
Wilkins J. N.
Publication year - 1987
Publication title -
acta psychiatrica scandinavica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.849
H-Index - 146
eISSN - 1600-0447
pISSN - 0001-690X
DOI - 10.1111/j.1600-0447.1987.tb02845.x
Subject(s) - sleep deprivation , psychology , mood , depression (economics) , sleep (system call) , psychiatry , sleep debt , clinical psychology , cognition , computer science , economics , macroeconomics , operating system
— To gain further insight into clinical associations seen in depression, the authors investigated the effect of interrupted night‐time sleep on the HPA axis and mood in 20 psychiatric house officers taking overnight call. Specific interest was in whether multiple awakenings could induce a positive DST. No statistically significant association emerged between number of nocturnal awakenings, number of hours of sleep deprivation or temporal occurrence of sleep deprivation and cortisol, DST or mood. The results suggest that cortisol and DST changes are not likely to be causally linked to, or epiphenomenon of disrupted sleep. The implications of these findings for major depression are discussed.