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Nuclear magnetic resonance imaging and single photon emission tomography with radio‐iodine labelled compounds in the diagnosis of dementia
Author(s) -
Ebmeier K. P.,
Besson J. A. O.,
Crawford J. R.,
Palin A. N.,
Gemmel H. G.,
Sharp P. F.,
Cherryman G. R.,
Smith F. W.
Publication year - 1987
Publication title -
acta psychiatrica scandinavica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.849
H-Index - 146
eISSN - 1600-0447
pISSN - 0001-690X
DOI - 10.1111/j.1600-0447.1987.tb02832.x
Subject(s) - dementia , magnetic resonance imaging , nuclear medicine , iodine 123 , medicine , cerebral blood flow , white matter , single photon emission computed tomography , positron emission tomography , alzheimer's disease , vascular dementia , emission computed tomography , radiology , pathology , disease
ABSTRACT— White matter lesions and T 1 changes were identified using NMR and then compared between groups of patients suffering from dementia of the Alzheimer type (DAT), Multiple infarct dementia (MID) and normal controls. All DAT and MID patients were also imaged with a gamma camera using 123 Iodo‐n‐isopropylamphetamine, a radiopharmaceutical whose uptake in the brain follows the regional blood flow. While NMR was not able to differentiate between DAT and MID, 19 out of 21 DAT patients compared to four out of 18 MID patients showed bilateral parietal lesions on IMP scans.