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Long‐term prognosis in addiction on sedative and hypnotic drugs analyzed with the Cox regression model
Author(s) -
Allgulander C.,
Ljungberg L.,
Fisher L. D.
Publication year - 1987
Publication title -
acta psychiatrica scandinavica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.849
H-Index - 146
eISSN - 1600-0447
pISSN - 0001-690X
DOI - 10.1111/j.1600-0447.1987.tb02828.x
Subject(s) - sedative , medicine , psychiatry , hypnotic , concomitant , sedative/hypnotic , proportional hazards model , addiction , substance abuse , alcohol abuse
— The prognosis of 221 patients first admitted in 1941–1954 for dependence on sedative‐hypnotic drugs was determined in a record‐linkage and interview study concluded in 1984. Different outcomes were related to admission characteristics by means of the Cox proportional hazards regression model. An excess of unnatural deaths was noted; suicides in 11% of the men and 23% of the women. Of those with primary sedative‐hypnotic dependence, 46% continued to abuse drugs till death or follow‐up, and of those with a primary or concomitant alcohol abuse 72%. An unfavorable outcome was significantly related to primary psychiatric symptoms before the first admission, concomitant alcohol abuse, familial drug and alcohol abuse and health care occupation.