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Side effects after disulfiram
Author(s) -
Christensen J. K.,
Rønsted P.,
Vaag U. H.
Publication year - 1984
Publication title -
acta psychiatrica scandinavica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.849
H-Index - 146
eISSN - 1600-0447
pISSN - 0001-690X
DOI - 10.1111/j.1600-0447.1984.tb02496.x
Subject(s) - disulfiram , placebo , medicine , side effect (computer science) , psychiatry , pharmacology , alternative medicine , pathology , computer science , programming language
– A double‐blind, randomized study was carried out on the side effects of disulfiram in 241 men and women with alcohol abuse. Of the 158 patients completing the study, 83 received disulfiram and 75 placebo. Each patient was questioned on side effects after a 2‐week wash‐out period and thereafter once a week during the 6‐week treatment period. There was no statistically significant difference between the two groups, apart from over‐representation of complaints of sexual problems in the placebo group. The patients who dropped out of the study were equally distributed between the two groups with regard to the number, diagnosis, and reasons for dropping out.