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Mental illness and sex chromosome aberration: renewed interest in light of a current survey
Author(s) -
Wahlström J.,
Axelsson R.
Publication year - 1984
Publication title -
acta psychiatrica scandinavica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.849
H-Index - 146
eISSN - 1600-0447
pISSN - 0001-690X
DOI - 10.1111/j.1600-0447.1984.tb01226.x
Subject(s) - karyotype , chromosome aberration , chromosome , population , y chromosome , etiology , x chromosome , psychiatry , medicine , genetics , psychology , biology , environmental health , gene
– Chromosome determination in 134 men with psychotic disorder revealed sex chromosome aberrations in three patients: one with karyotype 47, XXY, one with 47, XXY/46. XY, and one with 46, XY/45, XO. The frequency of sex chromosome changes in our population (2 %) was significantly increased compared to that, in newborns. Since sex chromosome aberrations may play an important role in the etiology of psychiatric disorders, chromosome determination should be included among the routine investigations of patients with psychotic symptoms.