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Recurrence of affective illness after withdrawal of long‐term lithium treatment
Author(s) -
Sashidharan S. P.,
McGuire R. J.
Publication year - 1983
Publication title -
acta psychiatrica scandinavica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.849
H-Index - 146
eISSN - 1600-0447
pISSN - 0001-690X
DOI - 10.1111/j.1600-0447.1983.tb06990.x
Subject(s) - discontinuation , lithium (medication) , psychiatry , bipolar disorder , psychology , depressive symptoms , medicine , cognition
– – Clinical outcome following discontinuation of long‐term maintenance therapy with lithium in manic‐depressive patients was studied. Although the majority showed recurrence of affective episodes, the relapses tended to be spread over a period of months. There was no evidence of immediate and inevitable ‘rebound’ of psychotic episodes following lithium withdrawal. This finding is discussed in the light of results from other lithium discontinuation studies.