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Indirectly acting neurotoxins
Author(s) -
Silbergeld E. K.
Publication year - 1983
Publication title -
acta psychiatrica scandinavica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.849
H-Index - 146
eISSN - 1600-0447
pISSN - 0001-690X
DOI - 10.1111/j.1600-0447.1983.tb00938.x
Subject(s) - neurochemical , neuroscience , central nervous system , brain function , porphyria , nervous system , hormone , psychology , medicine , physiology , endocrinology
The role of toxic substances in causing central nervous system dysfunction is discussed with a focus on effects which are mediated indirectly through other organ systems which affect the brain. Neurochemical measurements of brain function, and the use of neuropharmacological probes of behavior are presented with the examples of lead poisoning, as a case of chemical porphyria, and estrogenization, as a case of hormonal dysfunction.