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Peptic ulcer complaints in lithium‐treated and non‐lithium‐treated manic‐depressive patients
Author(s) -
Jepsen P. W.,
Jensen E.,
Pienge P.,
Rafaelsen O. J.
Publication year - 1983
Publication title -
acta psychiatrica scandinavica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.849
H-Index - 146
eISSN - 1600-0447
pISSN - 0001-690X
DOI - 10.1111/j.1600-0447.1983.tb00353.x
Subject(s) - lithium (medication) , peptic ulcer , manic depressive , medicine , gastroenterology , psychiatry
‐ A possible protective effect of lithium against the occurrence of peptic ulcer complaints in manic‐depressive patients, treated with lithium, was investigated. 167 manic‐depressive patients, 91 in lithium treatment, 76 not in lithium treatment, were questioned about clinical symptoms of peptic ulcer. Thirteen of the lithium‐treated and 23 of the non‐lithium‐treated patients reported symptoms of peptic ulcer. The difference was statistically significant. The hypothesis that lithium treatment reduces the frequency of symptoms of peptic ulcer in manic‐depressive patients was thus confirmed.