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A double‐blind comparison of nomifensine and amitriptyline in the treatment of depression
Author(s) -
Ong S. B. Y.,
Lee C. T.
Publication year - 1981
Publication title -
acta psychiatrica scandinavica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.849
H-Index - 146
eISSN - 1600-0447
pISSN - 0001-690X
DOI - 10.1111/j.1600-0447.1981.tb00668.x
Subject(s) - nomifensine , amitriptyline , tolerability , palpitations , antidepressant , depression (economics) , medicine , double blind , psychiatry , psychology , anesthesia , placebo , pharmacology , adverse effect , anxiety , alternative medicine , dopaminergic , pathology , economics , macroeconomics , dopamine
A double‐blind study was carried out to compare the efficacy and tolerability of nomifensine and amitriptyline in 17 Malaysian patients with moderate to severe depression. The two drugs did not differ with regard to antidepressant effect but nomifensine‐treated subjects report fewer side‐effects with no complaints of palpitations. Nomifensine also increases capacity for work and activity.