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The 24‐hour pattern of serum TSH in patients with endogenous depression
Author(s) -
Weeke A.,
Weeke J.
Publication year - 1980
Publication title -
acta psychiatrica scandinavica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.849
H-Index - 146
eISSN - 1600-0447
pISSN - 0001-690X
DOI - 10.1111/j.1600-0447.1980.tb00594.x
Subject(s) - endogeny , depression (economics) , medicine , endocrinology , endogenous depression , blood sampling , significant difference , serum concentration , circadian rhythm , psychology , economics , macroeconomics
The 24‐h pattern of serum thyrotropin (TSH) has been studied using hourly blood‐sampling in four patients with severe endogenous depression. All patients showed a pattern similar to that of normal subjects, with lowest levels of serum TSH between 0900 and 2000 h and highest levels between 2100 and 0800 h. A phaseshift of the TSH rhythm can therefore not account for our previous finding of a significant negative correlation between severity of endogenous depression and night increase in serum TSH measured as the difference between the values at 2400 and 1400 h.