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5‐Hydroxytryptamine content of the whole blood in psychiatric illness and alcoholism
Author(s) -
Banki C. M.
Publication year - 1978
Publication title -
acta psychiatrica scandinavica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.849
H-Index - 146
eISSN - 1600-0447
pISSN - 0001-690X
DOI - 10.1111/j.1600-0447.1978.tb06889.x
Subject(s) - mania , tricyclic , depression (economics) , psychiatry , schizophrenia (object oriented programming) , medicine , psychology , serotonin , bipolar disorder , lithium (medication) , pharmacology , macroeconomics , economics , receptor
5‐Hydroxytryptamine (5HT, serotonin) content of the whole blood has been measured in hospitalized groups of manic, depressed, schizophrenic and alcoholic patients; values were compared to non‐psychotic controls. Only depressives had significantly different values. Alcoholics occupied an intermediate position between depressives and controls. Schizophrenics had virtually the same average level. Manic patients showed a very weak tendency toward higher values. Neuroleptic drugs in mania did not alter the blood 5HT levels, but in depression tricyclic antidepressants caused an elevation after 3 weeks of treatment. These post‐treatment levels no longer differed significantly from those of non‐psychotic controls.