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Subjective effects and vigilance after diazepam and oxazepam in normal subjects
Author(s) -
GOTTESTAM K. G.,
ANDERSSON B. E.
Publication year - 1978
Publication title -
acta psychiatrica scandinavica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.849
H-Index - 146
eISSN - 1600-0447
pISSN - 0001-690X
DOI - 10.1111/j.1600-0447.1978.tb02396.x
Subject(s) - oxazepam , vigilance (psychology) , placebo , diazepam , psychology , medicine , anesthesia , psychiatry , benzodiazepine , neuroscience , receptor , alternative medicine , pathology
Twenty‐two normal subjects were given single oral doses of diazepam 5 mg, oxazepam 1.5 mg and placebo in a double‐blind cross‐over trial. Subjcctive effects according to a rating scale and performance on a vigilance task were assessed. The results showed a difference between each of the two drugs and placebo. but none between the drugs, with regard to the vigilance test. The results from the rating of subjective effects showed an increase in “tiredness for both drugs, and a decreased “well‐being for oxazepam.