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Effect of fusaric acid on tardive dyskinesia and mental state in psychogeriatric patients
Author(s) -
Viukari M.,
Linnoila M.
Publication year - 1977
Publication title -
acta psychiatrica scandinavica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.849
H-Index - 146
eISSN - 1600-0447
pISSN - 0001-690X
DOI - 10.1111/j.1600-0447.1977.tb06663.x
Subject(s) - fusaric acid , tardive dyskinesia , dyskinesia , akathisia , anxiety , trihexyphenidyl , medicine , psychiatry , psychology , anesthesia , schizophrenia (object oriented programming) , antipsychotic , parkinson's disease , disease , horticulture , fusarium , biology
The effect of fusaric acid 150–50 mg daily on tardive dyskinesia and mental state was studied in 15 chronic psychogeriatric patients. The patients' previous drug treatment was maintained unchanged during the experiment. Fusaric acid significantly relieved oro‐facial dyskinesia, tremor, and rigidity, and it improved the mental state of the patients (BPRS). Akathisia was exacerbated, but this change was not significant. Akinesia and anxiety were not altered.