Premium
Screening for cystoid macular oedema in children with uveitis using the retinal thickness analyser
Author(s) -
Maca Saskia M.,
Garhofer Gerhard,
Kiss Christopher,
BarisaniAsenbauer Talin
Publication year - 2008
Publication title -
acta ophthalmologica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.534
H-Index - 87
eISSN - 1755-3768
pISSN - 1755-375X
DOI - 10.1111/j.1600-0420.2007.01009.x
Subject(s) - medicine , ophthalmology , visual acuity , retinal , macular edema , uveitis , optometry
. Purpose: This study aimed to investigate the retinal thickness analyser (RTA) as a means to identify the presence of cystoid macular oedema (CMO) in children with uveitis, whether the course of CMO can be monitored using this method, and whether there is a trend towards a correlation between macular oedema and visual acuity (VA) in children. Methods: This prospective, cross‐sectional study with observer‐blinded analysis included 25 eyes. Standardized testing for best corrected distance VA (d‐VA), near (reading) VA (n‐VA) and slit‐lamp examination were conducted. Using the RTA, a 3 × 3‐mm scan of the macula was obtained, which was then used to discern CMO and calculate mean foveal thickness (MFT). Results: Macular scanning was possible in all children. Cystoid macular oedema was discerned in 10 eyes (40%) and ruled out in 15. In CMO eyes, d‐VA was 0.5 Snellen and n‐VA was 2 Jaeger; neither result differed significantly from those in eyes without CMO. Mean foveal thickness correlated with n‐VA ( r = 0.511, p = 0.015), but not with d‐VA ( r = 0.271, p = 0.191). After 3 months of tailored therapy, CMO was still detectable in six eyes. Changes in d‐VA in the CMO and non‐CMO groups were 3 ± 2.1 and 0.8 ± 1.8 Snellen, respectively; changes in n‐VA were 1 ± 1.4 and 0.1 ± 0.3 Jaeger, respectively. Changes in MFT were − 244.8 ± 137.4 µm and − 0.8 ± 18.1 µm, respectively. A statistically significant correlation was found between the changes in MFT and n‐VA ( r = 0.629), but not with that in d‐VA ( r = 0.292). Conclusions: We used the RTA to establish the presence or absence of CMO according to measurements of the macular region. Our findings show that CMO is a common complication in children with uveitis and can be present even in cases with good d‐VA. Mean foveal thickness as measured with the RTA correlates indirectly with n‐VA.