Open AccessVitreous fluorophotometry and changes in blood‐retinal barrier permeability induced by Bendazac lysine
Author(s) -
Nuzzi Giuseppe,
Venturini Ivan,
Gregorio Mauro,
Arsenio Leone,
Maraini Giovanni
Publication year - 1997
Publication title -
acta ophthalmologica scandinavica
Language(s) - English
Resource type - Journals
eISSN - 1600-0420
pISSN - 1395-3907
DOI - 10.1111/j.1600-0420.1997.tb00247.x
Subject(s) - medicine , placebo , ophthalmology , blood–retinal barrier , retinal , diabetic retinopathy , diabetes mellitus , endocrinology , pathology , alternative medicine
. Vitreous fluorophotometry was used to investigate the effect of Bendazac lysine on the blood retinal barrier in 12 insulin‐dependent diabetics with mild background retinopathy. The study was a randomized, double blind, cross‐over trial, drug versus Placebo. Each treatment period was of 4 months. The vitreous penetration coefficient was reduced by 21% (95% c.i. 12, 30; p = 0.001) by treatment with respect to Placebo.