
Maternal and neonatal outcomes of grand multiparas over two decades in Mali
Author(s) -
TEGUETE IBRAHIMA,
MAIGA AMELIA W.,
LEPPERT PHYLLIS C.
Publication year - 2012
Publication title -
acta obstetricia et gynecologica scandinavica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.401
H-Index - 102
eISSN - 1600-0412
pISSN - 0001-6349
DOI - 10.1111/j.1600-0412.2012.01372.x
Subject(s) - medicine , obstetrics , odds ratio , placental abruption , placenta previa , prenatal care , population , cross sectional study , pregnancy , maternal death , odds , fetus , logistic regression , placenta , environmental health , pathology , biology , genetics
Objective. To analyze the association between grand multiparity and maternal and neonatal morbidity and mortality. Design. Retrospective cross‐sectional study. Setting. Point G National Hospital, a tertiary care hospital in Bamako, Mali. Population. All singleton births from 1985 to 2003. Methods. Cross‐sectional study of 13 340 singleton births at a tertiary care hospital in Mali (1985–2003) compared outcomes between 3617 grand multiparas (para ≥5) and 9723 pauciparas (para 1–4). Odds ratios (OR) were adjusted for maternal age, prenatal care utilization, socioeconomic status, and region of origin. Main outcome measures. Maternal mortality, perinatal mortality, placental abnormalities (previa and abruption), uterine rupture, postpartum infection, postpartum hemorrhage, eclampsia, cesarean delivery, mean birthweight, low birthweight, high birthweight. Results. Grand multiparas were older, poorer, and less likely to have accessed prenatal care. Grand multiparas had a lower adjusted odds of maternal death (adjusted OR, 0.66; 95%CI, 0.45–0.97), but higher adjusted odds of perinatal death (adjusted OR, 1.33; 95%CI, 1.12–1.59), placental abnormalities (adjusted OR, 1.57; 95%CI, 1.21–2.05), and high birthweight (adjusted OR, 1.42; 95%CI, 1.05–1.92). Conclusions. The healthy person effect may explain grand multiparas’ lower odds of maternal death. Reducing grand multiparity and improving grand multiparas’ access to prenatal care may improve population‐level perinatal outcomes.