Open AccessLocal infiltration analgesia in urogenital prolapse surgery: a prospective randomized, double‐blind, placebo‐controlled study
Author(s) -
KRISTENSEN BILLY B.,
RASMUSSEN YVONNE H.,
AGERLIN MARIANNE,
TOPP MONICA W.,
WEINCKE MARIANNE O.,
KEHLET HENRIK
Publication year - 2011
Publication title -
acta obstetricia et gynecologica scandinavica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.401
H-Index - 102
eISSN - 1600-0412
pISSN - 0001-6349
DOI - 10.1111/j.1600-0412.2011.01234.x
Subject(s) - medicine , ropivacaine , anesthesia , analgesic , infiltration (hvac) , placebo , local anesthetic , opioid , surgery , randomized controlled trial , saline , physics , alternative medicine , receptor , pathology , thermodynamics
Objective. To evaluate the analgesic effect of high‐volume infiltration analgesia in urogenital prolapse surgery and provide a detailed description of the infiltration technique. Design. A randomized, double‐blind, placebo‐controlled study following the CONSORT criteria. Setting. A university hospital. Patients. 48 patients undergoing posterior wall repair and perineorraphy. Methods. Patients received high‐volume (26ml) ropivacaine 1% with epinephrine ( n =23) or saline ( n =22) infiltration using a systematic technique ensuring uniform delivery to all tissues incised, handled or instrumented during the procedure. Main outcome measures. Pain and opioid requirements were assessed for 24hours as well as time spent in the post‐anesthesia care unit and time to first mobilization. Results. Pain at rest, during coughing and movement was significantly reduced for the first four hours with the high‐volume local anesthetic infiltration technique ( p <0.001–0.006). Opioid requirements and time spent in the post‐anesthesia care unit were significantly reduced in the ropivacaine group ( p <0.001 and p <0.001, respectively) as well as the time to first mobilization ( p <0.014). Conclusion. Systematic high‐volume infiltration analgesia is an effective analgesic technique in patients undergoing posterior wall repair and perineorraphy, and improves early recovery.