Open AccessPlacental abruption and premature rupture of membranes
Author(s) -
MARKHUS VIBECKE HØGBERG,
RASMUSSEN SVEIN,
LIE STEIN ATLE,
IRGENS LORENTZ M.
Publication year - 2011
Publication title -
acta obstetricia et gynecologica scandinavica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.401
H-Index - 102
eISSN - 1600-0412
pISSN - 0001-6349
DOI - 10.1111/j.1600-0412.2011.01224.x
Subject(s) - prom , placental abruption , medicine , odds ratio , obstetrics , premature rupture of membranes , confidence interval , population , pregnancy , gestational age , gynecology , gestation , biology , environmental health , genetics
Objective . To assess whether premature rupture of membranes (PROM) is associated with placental abruption. Design . Population‐based study. Setting . Data were extracted from the Medical Birth Registry of Norway. Population . All women with PROM (18 889 cases), including 3 077 cases of preterm premature rupture of membranes (p‐PROM), among a total of 355 416 singleton births in Norway during 1999–2005 with gestational age 17–44weeks. Methods . Logistic regression was used to assess whether placental abruption was associated with PROM in preterm and term births. Main Outcome Measures . Placental abruption. Results . The occurrence of placental abruption in p‐PROM was higher than in the total study population, 11.0 per 1 000 (34 of 3 077) vs. 4.2 per 1 000 (1 495 of 355 416; adjusted odds ratio 2.6, 95% confidence interval 1.8–3.7). Restricting the analyses to preterm births, the occurrence of placental abruption was less in p‐PROM (11.0 per 1 000) than in births without p‐PROM (36.1 per 1 000; adjusted odds ratio 0.3, 95% confidence interval 0.2–0.4). In term births, no statistically significant association was observed. Conclusions . The findings suggest that in p‐PROM the risk of placental abruption is not higher than in other preterm births; rather the opposite. However, comparing the risks in p‐PROM and the total gestational age range, the present study confirmed results reported in previous studies of a higher risk of placental abruption in p‐PROM than in the total birth population.