Open AccessRecurrent early pregnancy loss and consanguinity in Omani couples
Author(s) -
GOWRI VAIDYANATHAN,
UDAYAKUMAR ACHANDIRA MUTHAPPA,
BSISO WAFA,
AL FARSI YAHAYA,
RAO KUNTAL
Publication year - 2011
Publication title -
acta obstetricia et gynecologica scandinavica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.401
H-Index - 102
eISSN - 1600-0412
pISSN - 0001-6349
DOI - 10.1111/j.1600-0412.2011.01200.x
Subject(s) - consanguinity , medicine , consanguineous marriage , miscarriage , recurrent miscarriage , obstetrics , pregnancy , family history , population , etiology , pediatrics , anti nuclear antibody , gynecology , surgery , immunology , antibody , genetics , environmental health , biology , autoantibody
Consanguinity is common in Arab countries. The Sultanate of Oman has a relatively small population with a high prevalence of consanguineous marriages. This is a retrospective study of women who had three or more consecutive miscarriages between January 2002 and December 2008, investigated in the non‐pregnant state. Age, parity, menstrual history, number of miscarriages, personal and family history, history of consanguinity and investigations were collected for 141 patients. The mean number of miscarriages was 3.4; 53% of the women had a consanguineous marriage, 42% were non‐consanguineous and in 5% the marital interrelationship was unknown. There was no significant difference in the prevalence of parental karyotype abnormalities, anticardiolipin antibodies, antinuclear antibodies, thyroid disorders, or lupus between the consanguineous and non‐consanguineous couples. Consanguinity appeared not to play a significant role in the etiology of recurrent spontaneous miscarriage.