Open AccessDehydroepi and Rosterone Sulfate in Saliva
Author(s) -
Lagrelius Anders,
Fridström Margareta,
Möllerström Gunnar,
Carlström Kjell
Publication year - 1988
Publication title -
acta obstetricia et gynecologica scandinavica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.401
H-Index - 102
eISSN - 1600-0412
pISSN - 0001-6349
DOI - 10.1111/j.1600-0412.1988.tb07815.x
Subject(s) - saliva , dehydroepiandrosterone sulfate , medicine , physiology , dehydroepiandrosterone , endocrinology , androgen , hormone
Abstract Concentrations of dehydroepiandrosterone sulfate (DHAS) in saliva and serum were determined in 11 healthy men aged 23–40yrs. 55 healthy, non‐medicated women aged 20–81 yrs and 13 healthy women aged 20–30 yrs, all taking combined oral contraceptives (OC). Serum DHAS was higher in men than in women of corresponding age and was negatively correlated to age in OC‐free women. These sex‐ and age‐related differences were not found for salivary DHAS. Salivary and serum DHAS values were poorly correlated and the ratios between salivary and serum DHAS were variable, with a tendency to higher values in older subjects. Low salivabrum DHAS ratios were found in OC users. The lack of a uniform, unequivocal relation between DHAS concentrations in saliva and serum renders salivary DHAS assays unsuitable for clinical purposes.