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Lambert–Eaton myasthenic syndrome following H1N1‐influenza vaccination – a case report
Author(s) -
Ansakorpi Hanna,
Rusanen Harri,
Rytky Seppo,
Färkkilä Markus
Publication year - 2012
Publication title -
acta neurologica scandinavica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.967
H-Index - 95
eISSN - 1600-0404
pISSN - 0001-6314
DOI - 10.1111/j.1600-0404.2012.01675.x
Subject(s) - vaccination , medicine , pandemic , outbreak , immunology , pediatrics , influenza a virus , virus , covid-19 , virology , disease , infectious disease (medical specialty)
Background The outbreak of influenza A (H1N1) pandemic during the year 2009 led to the development of several vaccinations against H1N1 virus. In Finland, 2.6 million citizens were vaccinated during pandemic 2009 – 2010 with adjuvanted influenza vaccine, Pandemrix ® . Clinical Presentation In this case report, we describe a patient with non‐paraneoplastic Lambert–Eaton myasthenic syndrome following Pandemrix ® vaccination. Conclusion Development of various autoimmune diseases in genetically predisposed subjects following exposure to certain environmental factors, including vaccinations, is a well‐known entity. Clinicians should be aware of the possibility of the induction of autoimmune diseases following vaccinations and actively ask the relevant clinical history in a newly diagnosed patient with an autoimmune disorder.

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