Premium
Sequelae following sural nerve biopsy in type 1 diabetic subjects
Author(s) -
Dahlin L. B.,
Lithner F.,
Bresäter L.E.,
Thomsen N. O. B.,
Eriksson K.F.,
Sundkvist G.
Publication year - 2008
Publication title -
acta neurologica scandinavica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.967
H-Index - 95
eISSN - 1600-0404
pISSN - 0001-6314
DOI - 10.1111/j.1600-0404.2008.01000.x
Subject(s) - medicine , biopsy , sural nerve , surgery , interquartile range , nerve biopsy , diabetes mellitus , type 2 diabetes , skin biopsy , peripheral neuropathy , endocrinology
Objectives – To detect post‐operative sequelae of sural nerve biopsy. Materials and methods–– A questionnaire mailed to type 1 diabetic patients ( n = 24; male/female 23/1; reply n = 23) 2 years after biopsy. Results – Type 1 diabetic patients (age 56 [11]; median [interquartile range]) had a long duration of diabetes (DM; 20 [19] years) and all had neuropathy. Three out of 24 patients developed infection (two superficial and one deep) and one had a post‐operative bleeding. Less frequent pain among the patients were reported from one centre. About one‐third or more of the patients still complained of pain, mostly mild, in the biopsy area and paraesthesia in the foot 2 years after surgery. More than two‐thirds of the patients were reluctant for further biopsy; a crucial information in drug trial planning. Conclusions – Sequelae of a sural nerve biopsy occur in type 1 DM. The risk for wound infections should be considered.