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Bone mass in elderly patients with Parkinson’s disease
Author(s) -
Lorefält B.,
Toss G.,
Granérus A.K.
Publication year - 2007
Publication title -
acta neurologica scandinavica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.967
H-Index - 95
eISSN - 1600-0404
pISSN - 0001-6314
DOI - 10.1111/j.1600-0404.2007.00875.x
Subject(s) - medicine , trochanter , bone mineral , parkinson's disease , body weight , bone density , osteoporosis , body mass index , bone mass , endocrinology , physical therapy , gastroenterology , disease
Objective – The objective of the present study was to find risk factors for low bone mineral density (BMD) in patients with Parkinson’s disease (PD). Material and methods – Twenty‐six PD patients and 26 age‐and sex‐matched healthy controls were assessed twice within a 1‐year period. PD symptoms, body weight, body fat mass, BMD, physical activity, smoking and serum concentrations of several laboratory analyses were investigated. Results – BMD in different locations was lower in PD patients compared with their controls and decreased during the investigated year. BMD was lower in PD patients with low body weight. BMD Z ‐score of trochanter in the PD group was directly correlated to the degree of physical activity and indirectly to the length of recumbent rest. Total body BMD Z ‐score in the PD group was directly correlated to the degree of rigidity. Serum 25‐hydroxy‐vitamin D was slightly lower in PD patients. Conclusion – Low body weight and low physical activity were risk factors for low BMD in PD, while rigidity seemed to be protective.