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Long‐term mortality among young ischemic stroke patients in western Norway
Author(s) -
WajeAndreassen U.,
Naess H.,
Thomassen L.,
Eide G. E.,
Vedeler C. A.
Publication year - 2007
Publication title -
acta neurologica scandinavica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.967
H-Index - 95
eISSN - 1600-0404
pISSN - 0001-6314
DOI - 10.1111/j.1600-0404.2007.00822.x
Subject(s) - ischemic stroke , medicine , stroke (engine) , term (time) , demography , cardiology , pediatrics , ischemia , mechanical engineering , engineering , physics , quantum mechanics , sociology
Objectives – To obtain data on long‐term mortality among young ischemic stroke patients compared with controls in this population‐based study. Material and methods – We used Kaplan–Meier survival analysis to compare 232 patients aged 15–49 years with first‐ever cerebral infarction in 1988–1997 and 453 controls followed from inclusion to death or 1 August 2005 for 2515 and 5558 person‐years respectively. In a subanalysis of 192 patients, we compared risk factor variables using the Kaplan–Meier method and log‐rank testing. We applied a Cox proportional hazards model to adjust for multiple risk factors. Results – Forty‐five patients and nine controls died during follow‐up ( P < 0.0005). Independent risk factors for mortality were active tumor disease ( P < 0.0005), high consumption of alcohol ( P < 0.0005), coronary atherosclerosis ( P < 0.001), living alone ( P < 0.02), seizures ( P < 0.04) and smoking ( P = 0.08). Conclusions – Long‐term mortality was significantly increased among young stroke patients, mainly due to such lifestyle factors as high consumption of alcohol and tobacco.