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Motor neuron disease recovery associated with IV ceftriaxone and anti‐Babesia therapy
Author(s) -
Harvey W. T.,
Martz D.
Publication year - 2007
Publication title -
acta neurologica scandinavica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.967
H-Index - 95
eISSN - 1600-0404
pISSN - 0001-6314
DOI - 10.1111/j.1600-0404.2006.00727.x
Subject(s) - ceftriaxone , amyotrophic lateral sclerosis , medicine , neuroborreliosis , mefloquine , babesia , motor neuron , borrelia burgdorferi , lyme disease , disease , babesiosis , immunology , antibiotics , virology , malaria , biology , chloroquine , antibody , microbiology and biotechnology
This report summarizes what we believe to be the first verifiable case of a significant and progressive motor neuron disease (MND) consistent with amyotrophic lateral sclerosis that resolved during treatment with i.v. ceftriaxone plus oral atovaquone and mefloquine. The rationale for use of these antibiotics was (i) positive testing for Borrelia burgdorferi and (ii) red blood cell ring forms consistent with Babesia species infection. The patient has continued to be free of MND signs and symptoms for 15 months, although some symptoms consistent with disseminated Borreliosis remain.