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Prothrombotic risk factors in ischemic stroke and migraine in children
Author(s) -
Pilarska E.,
Lemka M.,
Bąkowska A.
Publication year - 2006
Publication title -
acta neurologica scandinavica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.967
H-Index - 95
eISSN - 1600-0404
pISSN - 0001-6314
DOI - 10.1111/j.1600-0404.2006.00599.x
Subject(s) - migraine , medicine , etiology , stroke (engine) , neurology , ischemic stroke , pediatrics , pathogenesis , physical therapy , ischemia , psychiatry , mechanical engineering , engineering
Objective – To evaluate the contribution of antiphospholipid antibodies (aPL) and thrombomodulin (Thm) in the pathogenesis of stroke and migraine in children. Materials and methods – Ninety children were included in the study: 30 children (4–15 years) after an ischemic stroke of an unknown etiology; 30 migrainous patients (8–15 years), who were hospitalized in the Department of Developmental Neurology, Medical University of Gdansk, Poland, and 30 healthy children of the same age. Results – The statistical analysis showed an increase in the values of anticardiolipin antibodies (aCL), anti β 2‐glycoprotein 1 ( β 2‐GP1) and Thm in children with stroke and migraine than in the control group. The resultant values were higher, but stayed at standard. Conclusion – The possible role of prothrombotic factors in individual cases of pediatric stroke and migraine cannot be excluded.