Premium
Wide‐range C‐reactive protein efficacy in acute ischemic stroke patients
Author(s) -
ShenharTsarfaty S.,
Ben Assayag E.,
Bova I.,
Vered Y.,
Berliner S.,
Rogowski O.,
Shapira I.,
Bornstein N. M.
Publication year - 2006
Publication title -
acta neurologica scandinavica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.967
H-Index - 95
eISSN - 1600-0404
pISSN - 0001-6314
DOI - 10.1111/j.1600-0404.2005.00572.x
Subject(s) - medicine , erythrocyte sedimentation rate , fibrinogen , c reactive protein , stroke (engine) , white blood cell , acute stroke , ischemic stroke , gastroenterology , venous blood , surgery , ischemia , tissue plasminogen activator , inflammation , mechanical engineering , engineering
Objective – To compare the recently introduced wide‐range C‐reactive protein (wr‐CRP) with the widely used high‐sensitivity Behring Dade method (hs‐CRP) in acute stroke/transient ischemic attack (TIA) patients. Materials and methods – A total of 119 consecutive patients admitted to a tertiary medical center with acute ischemic stroke/TIA were included in the study. Venous blood was obtained for both assays during the first 24 h, 3–5 days, as well as 3–6 months thereafter. Results – A highly significant correlation ( r = 0.994, P < 0.0001) was found between the two methods even when analyzed at three different time points. In addition, a similar correlation was noted between these two assays and other commonly used biomarkers, including white blood cell count, Westergren's sedimentation rate and quantitative fibrinogen. Conclusion – Real‐time, on‐line and low‐cost wr‐CRP assay is a reasonable alternative to the Behring Dade hs‐CRP method in acute stroke/TIA patients.