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Body tempreture correlates with functional outcome and lesion size of cerebral infarction
Author(s) -
Fukuda H.,
Kitani M.,
Takahashi K.
Publication year - 1999
Publication title -
acta neurologica scandinavica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.967
H-Index - 95
eISSN - 1600-0404
pISSN - 0001-6314
DOI - 10.1111/j.1600-0404.1999.tb01057.x
Subject(s) - medicine , cardiology , atrial fibrillation , infarction , stroke (engine) , cerebral infarction , lesion , multivariate analysis , modified rankin scale , ischemia , surgery , ischemic stroke , myocardial infarction , mechanical engineering , engineering
‐ Experimental studies have demonstrated that mild hyperthermia exacerbates ischemia‐induced neuronal injury. Material and methods ‐ We examined the relationship between body temperature and functional outcome in 183 patients suffering from cerebral infarction, and admitted within 24 h from the onset of stroke. Patients’functional capacities in daily life were evaluated by Rankin's score before the attack (RS0), on the day of admission (RSI), and 3 months after the onset of stroke (RS90). Results ‐ RS90 showed an independent correlation with RS0, RSI, age, infarct size and maximum body temperature recorded within the first 7 days from the onset of stroke by multivariate analysis. History of previous cerebrovascular accidents, atrial fibrillation, hemorrhagic transformation, infection, and a hypothalamic lesion showed significant associations with RS90 by the Mann‐Whitney‐test, but not by multivariate analysis. Infarct size correlated with body temperature, atrial fibrillation, and hemorrhagic transformation. Conclusion ‐ Body temperature correlated well with both functional outcome and infarct size in patients with an acute cerebral infarction.