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Herpes simplex virus type 2 DNA detected in cerebrospinal fluid of 9 patients with Mollaret's meningitis
Author(s) -
Jensenius M.,
Myrvang B.,
Størvold G.,
Bucher A.,
Hellum K. B.,
Bruu A.L.
Publication year - 1998
Publication title -
acta neurologica scandinavica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.967
H-Index - 95
eISSN - 1600-0404
pISSN - 0001-6314
DOI - 10.1111/j.1600-0404.1998.tb07296.x
Subject(s) - aseptic meningitis , cerebrospinal fluid , medicine , herpes simplex virus , meningitis , virology , polymerase chain reaction , virus , herpesviridae , alphaherpesvirinae , viral disease , pediatrics , biology , gene , biochemistry
We present clinical and virological data on 9 patients, 7 women and 2 men aged 31–56 years, with recurrent aseptic meningitis (Mollaret's meningitis). Polymerase chain reaction detected Herpes simplex virus type 2 DNA in cerebrospinal fluid samples from all patients collected during their latest attacks of meningitis. Six patients had no history of genital herpes. Only 1 patient was offered prophylactic antiviral treatment during the study period (45 months).