Premium
Application of PET in dementia disorders
Author(s) -
Nordberg A.
Publication year - 1996
Publication title -
acta neurologica scandinavica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.967
H-Index - 95
eISSN - 1600-0404
pISSN - 0001-6314
DOI - 10.1111/j.1600-0404.1996.tb00377.x
Subject(s) - dementia , positron emission tomography , neuropsychology , neuroimaging , medicine , disease , pet imaging , cerebral blood flow , neuroscience , alzheimer's disease , psychology , cognition , pathology
Positron emission tomography (PET) is a valuable tool for understanding of functional correlates of biological and structural changes in brain of patients with various dementia diseases. As such it can provide valuable physiological correlates important for diagnosis, management and research of dementia disorders. A crucial question is whether PET is capable of early or preclinical detection of dementia. Longitudinal PET studies in Alzheimer families with chromosomal aberrations will be important for. Impairment of cerebral blood flow and glucose metabolism is a common feature in patients with Alzheimers disease. The pattern of changes in distinct from other forms of dementia and correlates with neuropsychological impairments. Neuroreceptor studies have to be further applied as well as monitoring of drug treatment effects.