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Contralateral temporal hypometabolism on positron emission tomography in temporal lobe epilepsy
Author(s) -
Nagarajan L.,
Schaul N.,
Eidelberg D.,
Dhawan V.,
Fraser R.,
Labar D. R.
Publication year - 1996
Publication title -
acta neurologica scandinavica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.967
H-Index - 95
eISSN - 1600-0404
pISSN - 0001-6314
DOI - 10.1111/j.1600-0404.1996.tb00178.x
Subject(s) - ictal , temporal lobe , positron emission tomography , epilepsy , magnetic resonance imaging , electroencephalography , temporal cortex , psychology , anterior temporal lobectomy , epilepsy surgery , medicine , neuroscience , radiology
— No detailed case studies report lateralised hypometabolism on positron emission tomography (PET) contralateral to the epileptogenic focus in temporal lobe epilepsy (TLE). Material and methods — We performed 18 F fluorodeoxyglucose (FDG) PET in two intractable TLE patients. Results — One had right temporal interictal spikes on electroencephalography (EEG) and a right medial temporal lobe lesion on magnetic resonance imaging (MRI). FDG‐PET showed decreased uptake in the left temporal lobe. Right temporal ictal onset, with bilateral interictal epileptiform activity, occurred on intracranial EEG. He is seizure free after right temporal lobectomy and ganglioglioma resection. The second had right temporal lobe interictal and ictal EEG activity. MRI demonstrated right anteriomedial temporal increased T2 signal. Neuropsychology revealed bilateral cognitive dysfunction. FDG‐PET showed left anterior temporal and lateral frontal hypometabolism. He is seizure free after right temporal lobectomy. Conclusion — These findings suggest that regional uptake asymmetry on FDG‐PET may be give misleading lateralising information in TLE.