Premium
Inhibitory motor seizures: correlation with centroparietal structural and functional abnormalities
Author(s) -
AbouKhalil B.,
Fakhoury T.,
Jennings M.,
Moots P.,
Warner J.,
Kessler R. M.
Publication year - 1995
Publication title -
acta neurologica scandinavica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.967
H-Index - 95
eISSN - 1600-0404
pISSN - 0001-6314
DOI - 10.1111/j.1600-0404.1995.tb00415.x
Subject(s) - ictal , electroencephalography , paralysis , psychology , neuroscience , epilepsy , neuroimaging , inhibitory postsynaptic potential , audiology , medicine , psychiatry
Six adults and 2 children with focal inhibitory motor seizures (ictal paralysis) were evaluated during a 4‐year period. Paresthesias at seizure onset occurred during some seizures in all patients, and focal clonic activity followed paralysis in 4. EEG‐CCTV recordings of the seizures in 2 patients showed that ictal paralysis coincided with an ictal discharge starting in one centroparietal area. MRI showed centroparietal structural lesions in six patients. One patient with a normal MRI scan had right centroparietal hypometabolism on PET. Inhibitory motor seizures must be differentiated from transient ischemic attacks and migraine. In our patients a centroparietal epileptogenic focus was suggested by neuroimaging studies, and in 2 instances by ictal EEG.