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A 15‐year follow‐up of phenytoin‐induced unilateral gingival hyperplasia: a case report
Author(s) -
Tigaran S.
Publication year - 1994
Publication title -
acta neurologica scandinavica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.967
H-Index - 95
eISSN - 1600-0404
pISSN - 0001-6314
DOI - 10.1111/j.1600-0404.1994.tb02739.x
Subject(s) - phenytoin , medicine , carbamazepine , hyperplasia , oral hygiene , gingival enlargement , epilepsy , dentistry , psychiatry
– The aim of this case report is to present a 15‐year follow‐up of a patient with phenytoin (PHT) intoxication with unilateral gingival hyperplasia (GH). Material and methods – A 50‐year‐old woman was followed‐up for 15 years clinically and paraclinically after a heavy PHT intoxication. Her immunoglobulins in serum were checked on PHT and after 15 years treatment with carbamazepine. Results – A gross mass of hyperplasia tissue found primarily in the left side of her mouth had disappeared and serum IgA which was subnormal at the first visit had normalized. Conclusion – It is possible to prevent GH from PHT treatment by intensive dental care, correct mouth hygiene and by change of treatment of carbamazepine.

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