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Severe axonal polyneuropathy with onset in the postpartum period
Author(s) -
Vital A.,
Larrivière M.,
Lagueny A.,
Ellie E.,
Ferrer X.,
Dupon M.,
Barat M.,
Mazaux J. M.
Publication year - 1994
Publication title -
acta neurologica scandinavica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.967
H-Index - 95
eISSN - 1600-0404
pISSN - 0001-6314
DOI - 10.1111/j.1600-0404.1994.tb01685.x
Subject(s) - wallerian degeneration , axonal degeneration , medicine , polyneuropathy , polyradiculoneuropathy , nerve biopsy , postpartum period , pregnancy , surgery , pathology , peripheral neuropathy , guillain barre syndrome , pediatrics , endocrinology , diabetes mellitus , biology , genetics
We report two patients who presented severe polyneuropathy in the postpartum period. Electrophysiological studies evidenced an axonal process which was associated with proximal demyelination in the second patient. In both cases, a peripheral nerve biopsy showed severe axonal Wallerian‐like degeneration and no feature of demyelination. The first patient had a dramatic loss of myelinated fibres, and severe disability persisted for several months. These two patients are different from cases of acute or chronic inflammatory demyelinating polyradiculoneuropathy previously reported in relation with pregnancy.