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Bipolar affective disorder prior to the onset of multiple sclerosis
Author(s) -
Hutchinson M.,
Stack J.,
Buckley P.
Publication year - 1993
Publication title -
acta neurologica scandinavica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.967
H-Index - 95
eISSN - 1600-0404
pISSN - 0001-6314
DOI - 10.1111/j.1600-0404.1993.tb05365.x
Subject(s) - multiple sclerosis , etiology , bipolar disorder , psychiatry , bipolar illness , epidemiology , psychology , medicine , clinical psychology , association (psychology) , age of onset , disease , cognition , mania , psychotherapist
The frequent association of affective disorder and multiple sclerosis raises important aetiological and clinical considerations. Reported here are seven patients who presented with symptoms of multiple sclerosis and who had a preceding history of bipolar affective disorder. The hypothesis that bipolar illness may be the initial manifestation of multiple sclerosis is discussed with reference to relevant clinical and epidemiological research on the topic.