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Total reaction time: a new approach in early HIV encephalopathy?
Author(s) -
Dunlop O.,
Bjørklund R.,
Abdelnoor M.,
Myrvang B.
Publication year - 1993
Publication title -
acta neurologica scandinavica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.967
H-Index - 95
eISSN - 1600-0404
pISSN - 0001-6314
DOI - 10.1111/j.1600-0404.1993.tb05355.x
Subject(s) - neuropsychology , human immunodeficiency virus (hiv) , cognition , medicine , encephalopathy , disease , pediatrics , psychiatry , immunology
In an attempt to develop better methods for diagnosis, screening and serial assessment of HIV‐1‐associated cognitive/motor complex, we have added a motor component to tests of reaction time, defining the new parameter as total reaction time. Thirty‐four non‐drug‐using, HIV‐positive men underwent four different tests of total reaction time. All four tests reached a level of statistical significance, both for a group of patients with early disease and for a group of patients with symptoms, compared with a control group. Total reaction time had a better discriminatory ability than standard reaction time, particularly for patients with early disease. It is suggested that neuropsychological studies of HIV‐1‐associated cognitive/motor complex should include tests of total reaction time.