Premium
Cerebrospinal fluid and MRI findings in three patients with multiple sclerosis and systemic lupus erythematosus
Author(s) -
Kinnunen E.,
Müller K.,
Keto P.,
Ketonen L.,
Helve T.,
Sepponen R.
Publication year - 1993
Publication title -
acta neurologica scandinavica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.967
H-Index - 95
eISSN - 1600-0404
pISSN - 0001-6314
DOI - 10.1111/j.1600-0404.1993.tb04117.x
Subject(s) - multiple sclerosis , cerebrospinal fluid , magnetic resonance imaging , medicine , pathology , white matter , hyperintensity , systemic lupus erythematosus , lupus erythematosus , radiology , immunology , disease , antibody
Three patients fulfilling the diagnostic criteria of both multiple sclerosis (MS) and systemic lupus erythematosus (SLE) were examined clinically, immunologically and by magnetic resonance imaging (MRI). In all three patients MRI showed several high‐signal lesions compatible with MS and, additionally, non‐specific small white matter lesions suggesting small vessel occlusion were seen. In CSF the cytoimmunological abnormalities were variable and showed only slight to moderate immunoactivation within the CNS at the time of sampling.