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Hepatitis A post‐viral encephalitis
Author(s) -
Davis L. E.,
Brown J. E.,
Robertson B. H.,
Khanna B.,
Polish L. B.
Publication year - 1993
Publication title -
acta neurologica scandinavica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.967
H-Index - 95
eISSN - 1600-0404
pISSN - 0001-6314
DOI - 10.1111/j.1600-0404.1993.tb04078.x
Subject(s) - virology , encephalitis , jaundice , antibody , hepatitis , hepatitis a , medicine , viral encephalitis , immunoglobulin m , virus , hepatitis c virus , cerebrospinal fluid , viral hepatitis , japanese encephalitis , immunology , hepatitis e virus , immunoglobulin g , biology , pathology , gastroenterology , genotype , biochemistry , gene
We report a seven‐year‐old girl who developed a hepatitis A viral infection and encephalitis. The patient developed fever, abdominal pains and jaundice. Five days later she became delirious, combative, and did not respond to verbal commands. Laboratory studies showed elevated liver enzymes and elevated serum immunoglobulin M (IgM) and immunoglobulin G (IgG) antibodies to hepatitis A virus. Cerebrospinal fluid contained IgG antibodies to hepatitis A virus but not IgM antibodies. Polymerase chain reaction, which amplifies a portion of the hepatitis A virus genome, did not demonstrate viral nucleic acid in cerebrospinal fluid. These studies suggest that the patient may have suffered from a post‐viral hepatitis A encephalitis from which she fully recovered.