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Slowly progressive limb‐kinetic apraxia with a decrease in unilateral cerebral blood flow
Author(s) -
Okuda B.,
Tachibana H.,
Kawabata K.,
Takeda M.,
Sugita M.
Publication year - 1992
Publication title -
acta neurologica scandinavica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.967
H-Index - 95
eISSN - 1600-0404
pISSN - 0001-6314
DOI - 10.1111/j.1600-0404.1992.tb08058.x
Subject(s) - apraxia , cerebral blood flow , lesion , posterior parietal cortex , single photon emission computed tomography , medicine , central nervous system disease , basal ganglia , supplementary motor area , psychology , neuroscience , cardiology , central nervous system , radiology , pathology , aphasia , functional magnetic resonance imaging
We report two patients with slowly progressive motor disorders, whose principal manifestations were asymmetric limb‐kinetic apraxia and muscle rigidity. In both patients MRI revealed no responsible lesion, whereas single photon emission computed tomography (SPECT) showed a decrease in cerebral blood flow (CBF) in the unilateral hemisphere. One patient with mainly right‐sided apraxia had a decreased CBF in the left central region between the frontal and parietal cortices, and the other patient with left‐sided apraxia in the right parietal cortex. In agreement with asymmetric clinical symptoms, the regional CBF decrease in the unilateral cortical areas including the frontal and parietal cortices may suggest a degenerative disease, presumably diagnosed as having corticobasal degeneration.