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Deblocking effect of TRH‐T in three cases of chronic progressive multifocal neuropathy
Author(s) -
Pinelli P.,
Pisano F.,
Miscio G.,
Ceriani F.
Publication year - 1992
Publication title -
acta neurologica scandinavica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.967
H-Index - 95
eISSN - 1600-0404
pISSN - 0001-6314
DOI - 10.1111/j.1600-0404.1992.tb05127.x
Subject(s) - polyradiculoneuropathy , medicine , anesthesia , pediatrics , guillain barre syndrome
Three cases of acquired demyelinating multifocal neuropathy with persistent conduction blocks are reported. In one of them protyreline tartrate (TRH‐T) had an evident deblocking effect; similar but milder effects were seen in the other two cases. The course and consistency of this effect is analyzed on the grounds of clinical and electromyographic findings. The nature of the THR‐T responsive conduction block is analysed as a mild variant of CIDP with regard to its occurrence in a late and chronic phase without signs of active immune processes.