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Risk factors for transient ischemic attacks in middle‐age. A population‐based case‐control study
Author(s) -
Fratiglioni L.,
Inzitari D.,
Arfaioli C.,
Nencini P.,
Ginanneschi A.,
Pracucci G.,
Zuppiroli A.,
Italian G.,
Amaducci L.
Publication year - 1991
Publication title -
acta neurologica scandinavica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.967
H-Index - 95
eISSN - 1600-0404
pISSN - 0001-6314
DOI - 10.1111/j.1600-0404.1991.tb04685.x
Subject(s) - odds ratio , confidence interval , medicine , incidence (geometry) , population , risk factor , diabetes mellitus , demography , endocrinology , physics , environmental health , optics , sociology
A case‐control study was based on “unselected” transient ischemic attacks (TIAs) in a middle‐aged Italian population. The identified cases included 52 prevalent and 25 incident TIAs. There was an incidence rate ratio (female/male) of 1.8 for definite cases. Comparison with the whole population for medical history of hypertension, diabetes and heart attack showed age/sex‐adjusted odds ratios of 4.3, 2.1, 7.9 for incident cases. The results were similar when a more detailed investigation of risk factors was performed with all the cases and a random sample of the controls. Moreover, female sex had an odds ratio for incident cases of 3.3 (95% confidence interval 1.0–11.3) after adjustment for age and presence of all the main risk factors. The presence of at least one cardiopathy showed an odds ratio of 8.3 for incident cases (95% confidence interval 2.4–28.4).