Premium
Alterations of nocturnal sleep in patients with HIV infection
Author(s) -
Wiegand M.,
Möller A. A.,
Schreiber W.,
Krieg J.C.,
Holsboer F.
Publication year - 1991
Publication title -
acta neurologica scandinavica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.967
H-Index - 95
eISSN - 1600-0404
pISSN - 0001-6314
DOI - 10.1111/j.1600-0404.1991.tb04664.x
Subject(s) - sleep (system call) , polysomnography , slow wave sleep , medicine , latency (audio) , sleep onset latency , nocturnal , sleep stages , non rapid eye movement sleep , sleep onset , insomnia , anesthesia , psychology , electroencephalography , psychiatry , operating system , computer science , electrical engineering , engineering
Nocturnal sleep of 14 patients with HIV infection was characterized by longer sleep onset latency, shorter total sleep time, reduced sleep efficiency, more time spent awake and in Stage 1. There was significantly less sleep Stage 2 than in healthy controls. REM latency was slightly reduced and correlated negatively with depressive symptomatology, while percentages of REM and slow wave sleep were normal. Patients without complaints at the time of the investigation exhibited similar sleep abnormalities. The results stress the usefulness of polysomnography as a sensitive methodology for detection and monitoring of CNS affection in HIV positive patients.