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Serum lipoprotein pattern variations in dementia and ischemic stroke
Author(s) -
Giubilei F.,
D'Antona R.,
Antonini R.,
Lenzi G. L.,
Ricci G.,
Fieschi C.
Publication year - 1990
Publication title -
acta neurologica scandinavica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.967
H-Index - 95
eISSN - 1600-0404
pISSN - 0001-6314
DOI - 10.1111/j.1600-0404.1990.tb00936.x
Subject(s) - dementia , medicine , cholesterol , stroke (engine) , apolipoprotein b , lipoprotein , cerebral infarction , apolipoprotein e , ischemic stroke , endocrinology , very low density lipoprotein , vascular dementia , cardiology , ischemia , disease , mechanical engineering , engineering
Blood levels of triglycerides, total cholesterol, isolated lipoprotein fractions (VLDL‐ LDL‐ and HDL‐cholesterol) and apoproteins (Apo‐A1 and Apo‐B) were examined in multi‐infarct dementia, senile dementia of the Alzheimer type, ischemic stroke associated with carotid atherosclerosis and in control subjects. Forty patients divided into 10 consecutive patients for each group were studied. Alzheimer patients showed mean total cholesterol and Apo‐B values significantly higher than control subjects. Apo‐B was significantly higher in stroke patients than in controls. The mean lowest HDL‐cholesterol (HDL‐c) value was observed in stroke patients. No significant differences in mean HDL‐c levels were found between patients with multi‐infarct and Alzheimer dementia.