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Early Stages of Late Onset Alzheimer's Disease
Author(s) -
Hellström Åke,
Forssell Lars G.,
Fernaeus SvenErik,
Hellström Åke
Publication year - 1989
Publication title -
acta neurologica scandinavica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.967
H-Index - 95
eISSN - 1600-0404
pISSN - 0001-6314
DOI - 10.1111/j.1600-0404.1989.tb04878.x
Subject(s) - audiology , psychology , dementia , alzheimer's disease , disease , perception , cognition , developmental psychology , physical medicine and rehabilitation , medicine , neuroscience
Psychometric profiles of 18 patients with Alzheimer's disease (AD). late onset type, and of 13 healthy control subjects were compared. Clear achievement reductions were found for the late onset AD patients in tests of face recognition and continuously measured reaction time (simple as well as choice). Also, the new time‐order error (TOE) test was utilized. From comparisons between computer‐presented successive stimuli, this test yields scores indicating basic perceptual/cognitive processes, as well as achievement scores. The TOE‐test results indicated a lowered capacity of attention and of perceptual adaptation in the late onset AD patients for tone duration, but not for line length. A comparison with a previous study of solvent‐related brain dysfunction suggests the potential value of TOE tests for differential diagnosis in dementia.